What is Immunoglobulin E (IgE)?
Immunoglobulin E (IgE) is a type of antibody produced by the immune system. In healthy individuals, IgE is present in very small amounts in the blood. However, in people with allergies or certain parasitic infections, IgE levels are significantly elevated. Testing total IgE levels helps doctors identify allergic conditions and guide appropriate treatment.
Why is the IgE Test Done?
- To investigate suspected allergic conditions such as allergic asthma, hay fever, allergic rhinitis, or eczema.
- To evaluate food allergies — especially in children with unexplained skin reactions, digestive problems, or breathing difficulties after eating.
- To check for parasitic infections (worm infections), which commonly raise IgE in Bangladesh.
- As part of investigating chronic urticaria (hives) or recurrent anaphylaxis.
- To monitor response to allergy treatment or immunotherapy.
Normal IgE Levels
Normal total IgE levels vary by age:
- Adults: Less than 100–150 IU/mL (varies by laboratory reference range)
- Children: Lower ranges, increasing with age
Elevated IgE alone does not confirm a specific allergy. If allergy is suspected, specific IgE tests (for individual allergens like dust mites, pollen, or specific foods) or a skin prick test are needed for precise identification.
How to Prepare for the IgE Test
No fasting or special preparation is required. Inform your doctor if you are taking antihistamines, corticosteroids, or immunosuppressant medications, as these may affect results. The test is a simple blood draw.